IMPROVED ONE POT PROCESS FOR SYNTHESIS OF BUSPIRONE BASE

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专利权人:

发明人:

DR AJIT MADHUKAR BHOBE,DR JAGANNATH BHAGAWANROA LAMTURE,DR TRYAMBAK MURLIDHAR SONAR,MR YASHWANT SHAMBHAJIRAO SURVE,MR NAVNATH BHAUSAHEB SHINDE,MR DEVIDAS MADHAVRAO PATIL

申请号：

IN1860/MUM/2011

公开号：

IN2011MU01860A

申请日:

2011.06.28

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

The present invention relates to an improved one-pot process for the preparation of pure Buspirone base. The said process involves the step of condensation of 1-(2-pyrimidinyl)-piperazine, 1,4-dibromobutane and 3,3-tetramethylene glutarimide in presence of an inorganic base and in an organic solvent.

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