Pyrrolo [2,1-C]1,4]naphthodiazepine linked piperazine compounds and a process for the preparation therof

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专利权人:

COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH

发明人:

申请号：

GB201309036

公开号：

GB201309036D0

申请日:

2012.01.10

申请国别(地区):

GB

年份:

2013

代理人:

摘要：

The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R&prime；=(Formula II). n=1-9 and R&Prime；=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl.

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