Arutla Viswanath;Jayanti Naga Srirama Chandra Murty;Ahmed Kamal
发明人:
Ahmed Kamal,Jayanti Naga Srirama Chandra Murty,Arutla Viswanath
申请号：
US13985510
公开号：
US08759339B2
申请日:
2012.01.10
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R′=(Formula II). n=1-9 and R″=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl.
