Process for preparing 1-[2-(2,4-dimethylphenysulfanyl)-pheny]piperazine or pharmaceutically acceptable salt thereof

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专利权人:

H. Lundbeck A/S

发明人:

Andre Faldt,Lone Munch Ringgaard,Michael J. Mealy,Michael Harold Rock,Jorgen Brodersen,Morten Jorgensen

申请号：

US14472896

公开号：

US09095588B2

申请日:

2014.08.29

申请国别(地区):

US

年份:

2015

代理人:

摘要：

This disclosure relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or a salt thereof. The process includes reacting compound II with compound III and compound IVin the presence of a solvent, a base and a palladium catalyst. R, R′, X1, and X2 in the formulas above are defined in the Specification.

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