PROBLEM TO BE SOLVED: To provide an inhibitor for the carbonylation of biological protein.SOLUTION: The present invention provides (a) a carbonylation inhibitor containing glucosinolate as an active ingredient; (b) the carbonylation inhibitor described in (a), where the glucosinolate is derived from broccoli seeds; and (c) the carbonylation inhibitor of (a) or (b), where the glucosinolate is at least one selected from (1) glucoiberin, (2) glucoraphanin, (3) glucoalyssin, (4) glucohesperin, (5) glucosiberin, (6) glucoerucin, and (7) glucoberteroin. The present invention also provides an inhibitor for the yellowing of dermis, containing the carbonylation inhibitor as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】生体タンパク質のカルボニル化抑制剤の提供。【解決手段】1.グルコシノレートを有効成分とする、カルボニル化抑制剤;2.前記グルコシノレートは、ブロッコリー種子由来のものである、上記1.に記載のカルボニル化抑制剤;3.前記グルコシノレートは、(1)glucoiberin、(2)glucoraphanin、(3)glucoalyssin、(4)glucohesperin、(5)glucosiberin、(6)glucoerucin、(7)glucoberteroinから選ばれる少なくとも1種である、上記1.又は上記2.のカルボニル化抑制剤。前記カルボニル化抑制剤を有効成分とする、真皮の黄ぐすみ抑制剤。【選択図】なし