A system and method for planning a pathway through an anatomical luminalnetworkof a patient including a computing device having at least one processor; adisplaydevice in communication with the computing device; and a user interfaceconfiguredfor display on the display device and configured to guide a user through apathwayplanning procedure. The user interface includes a patient selection windowconfigured to receive a user input to select a patient having CT image data onwhichto perform pathway planning; a target selection window configured to receive auserinput to select at least one target from the CT image data; and an airwayfinderwindow configured to generate at least one pathway from the at least onetarget toan entry point of the anatomical luminal network in response to a user input.