SPANGENBERG, GERMAN,EMMERLING, MICHAEL,ONG, ENG KOK,MENDEZ, RAMIRO,PANTER, STEPHEN,LABANDERA, MARCEL
申请号：
NZ59271204
公开号：
NZ592712A
申请日:
2004.04.14
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
Disclosed is a substantially purified or isolated citrate synthase polypeptide including an amino acid sequence selected from the group consisting of sequences shown in Figures 100, 115, 119 and 123 hereto (SEQ ID NOS 328, 350, 352 and 354 respectively)； and functionally active variants thereof having at least approximately 90% identity to the recited sequences. Further disclosed is a substantially purified or isolated nucleic acid or nucleic acid fragment encoding citrate synthase (CS), or complementary or antisense to a sequence encoding CS, and including a nucleotide sequence selected from the group consisting of (a) sequences shown in Figures 99, 101, 114, 118 and 122 hereto (SEQ ID NOS 327, 329 to 335, 349, 351 and 353 respectively)； (b) complements of the sequences recited in (a)； (c) sequences antisense to the sequences recited in (a) and (b)； (d) functionally active fragments and variants having at least approximately 95% identity to the functional part of the sequences recited in (a), (b) and (c) and having a size of at least 60 nucleotides； and (e) RNA sequences corresponding to the sequences recited in (a), (b), (c) and (d).
