Chia-Lin LEE;Jau-Shyang HUANG;Yi-Cheng LI;Feng-Ching HSIEH;Ying-Chen LU
发明人:
Ying-Chen LU,Jau-Shyang HUANG,Feng-Ching HSIEH,Yi-Cheng LI,Chia-Lin LEE
申请号：
US13006432
公开号：
US20120183504A1
申请日:
2011.01.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A use of probiotic strain GM-263 (ADR-1) in treating renal fibrosis in diabetes is disclosed. The probiotic strain such as Lactobacillus renteri strain GM-263 (ADR-1) (accession No. CCTCC M 209263) is utilized to produce a composition for treating renal fibrosis in diabetes in an effective dose, thereby reducing the concentration of glycated hemoglobin and blood sugar and keeping body weight and kidney weight within normal range, as well as specifically inhibiting phosphorylation of JAK2/STAT1 signal transduction pathway and renal fibrosis-related protein expression.
