SPANO MARIA CARLOTTA;CALDRER SARA;DOMINICI MASSIMO;PAOLUCCI PAOLO
发明人:
BESTAGNO MARCO,CALDRER SARA,CAMPANA DARIO,DOMINICI MASSIMO,PAOLUCCI PAOLO,SPANO MARIA CARLOTTA
申请号：
ITMO20110270
公开号：
ITMO20110270A1
申请日:
2011.10.25
申请国别(地区):
IT
年份:
2013
代理人:
摘要：
A modified effector cell includes a non-reversibly produced vector-encoded anti-GD2-BB-ζ chimeric receptor for use in disialoganglioside GD2-expressing neoplasia, which is inserted in the cell, to obtain an effector cell that stably produces the anti-GD2-BB-ζ chimeric receptor, the chimeric receptor having two distinct mutually fused portions, i.e. an intra-cytoplasmic portion and an extra-cytoplasmic portion.
