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pharmaceutical composition, lyophilized composition, process for manufacturing a pharmaceutical composition, methods for treating a cellular proliferative disorder in a patient and for imaging and detecting a cellular proliferative disorder in a patient, and, composition for detecting and imaging a cellular proliferative disorder. in a patient
专利权人:
GENSPERA; INC.
发明人:
Andrew X. Chen,Yali Tsai
申请号：
BR112015008421
公开号：
BR112015008421A2
申请日:
2013.10.14
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
1/1 summary â € œpharmaceutical composition, freeze-dried composition, process for making a pharmaceutical composition, methods for treating a cell proliferative disorder in a patient and for imaging and detecting a cell proliferative disorder in a patient , and, composition for detecting and imaging a cell proliferative disorder in a patient. Therapeutic prodrug compositions which can be delivered to a patient via an emulsion are provided herein. which comprises a peptide-linked therapeutic drug that is efficiently and specifically cleaved by a selected protease associated with a cell proliferative disorder, including cancer cells, for example, cancer cells. prostate, fan or breast in a patient. Also provided herein are methods of treating cellular proliferative disorders, including cancers, with the therapeutic prodrug compositions.1 / 1 resumo “composiã‡ãƒo farmacãšutica, composiã‡ãƒo liofilizada, processo para fabricar uma composiã‡ãƒo farmacãšutica, mã‰todos para tratar um distãšrbio proliferativo celular em um paciente e para formar imagem e detectar um distãšrbio proliferativo celular em um paciente, e, composiã‡ãƒo para detectar e formar imagem de um distãšrbio proliferativo celular em um pacienteâ€� sã£o fornecidas aqui composiã§ãµes de prã³-medicamento terapãªuticas que podem ser liberadas a um paciente por intermã©dio de uma emulsã£o injetã¡vel, que compreende um medicamento terapãªutico ligado a um peptãdeo que ã© clivado de maneira eficiente e especãfica por uma protease selecionada associada com um distãºrbio proliferativo celular, incluindo cã©lulas cancerãgenas, por exemplo, cã©lulas de cã¢ncer de prã³stata, fãgado ou mama, em um paciente. tambã©m sã£o fornecidos aqui mã©todos de tratar distãºrbios proliferativos celulares, incluindo cã¢nceres, com as composiã§ãµes de prã³-medicamento terapãªuticas.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
