The present invention relates to the field of pharmaceutical chemistry. Disclosed are a new amorphous piceatannol 3-O-glucoside, preparation method thereof, and pharmaceutical composition containing the same. The amorphous piceatannol 3-O-glucoside has favorable performances in stability and solubility. The preparation method for the amorphous piceatannol 3-O-glucoside in the present invention is easy to operate, and the resulting product has a high yield, and is suitable for development of a laboratory and industrial production, thus having a wide application. The amorphous piceatannol 3-O-glucoside product prepared by the method in the present invention has a stable quality, a favorable solubility, and can be directly used to prepare medicine treating cardiovascular diseases and cerebrovascular diseases.
