Zhang, Mingqiang,Wilkinson, Barrie,Beckmann, Christoph Hendrik,Moss, Steven James,Sheridan, Rose Mary
申请号：
AU2006221786
公开号：
AU2006221786B2
申请日:
2006.03.10
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to novel 39-desmethoxyrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxyrapamycin derivatives in the treatment of cancer and / or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.
