BECKMANN, CHRISTOPH HENDRIK,MOSS, STEVEN JAMES,SHERIDAN, ROSE MARY,ZHANG, MINGQIANG,WILKINSON, BARRIE
申请号：
CA2600640
公开号：
CA2600640C
申请日:
2006.03.10
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to novel 39-desmethoxyrapamycin derivatives,methods for their production, and uses thereof. In a further aspect thepresent invention provides for the use of these 39-desmethoxyrapamycinderivatives in the treatment of cancer and / or B-cell malignancies, theinduction or maintenance of immunosuppression, the treatment oftransplantation rejection, graft vs. host disease, autoimmune disorders,diseases of inflammation, vascular disease and fibrotic diseases, thestimulation of neuronal regeneration or the treatment of fungal infections.
