The present invention provides the orally disintegrating tablet comprisingNabilone or apharmaceutically acceptable salt thereof, wherein said tablet show rapidlydisintegrating abilityin an oral cavity within up to 30 seconds, solubility and proper hardness.Further is disclosed amethod of manufacturing the ODT comprising nabilone that is suitable for usein treatment ofpatients with nausea and dysphasia problems associated with cancer undergoingchemotherapy.