БУВЬЕ Ги (FR),ЛЕОНИ Мэттью Джеймс (US),ГРАБЕР Майкл (US)
申请号:
RU2013125033/15
公开号:
RU2013125033A
申请日:
2011.06.29
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A method of preventing the formation of skin cancer in a subject comprising administering to the subject a composition comprising an effective amount of agonist, α-adrenergic receptor and a pharmaceutically acceptable nositel.2. A method of inhibiting the progression of existing dermal tumors in a subject comprising administering to the subject a composition comprising a therapeutically effective amount of the agonist of α-adrenergic receptor and a pharmaceutically acceptable nositel.3. A method of inducing death or inhibiting the growth of tumor cells of the skin, comprising contacting the skin of the tumor cells with a composition comprising an agonist of adrenergic α-receptor in an amount sufficient to cause death or to suppress tumor growth kletok.4 skin. A method of skin protection, skin or lips of the subjects head from the harmful effects of UV radiation, comprising administering to the subject a composition comprising a safe and effective amount of α-adrenergic agonist retseptora.5. subjects skin tanning method comprising administering to the subject a composition comprising a safe and effective amount of α-adrenergic agonist retseptora.6. A method according to any one of claims. 1-5, where the α-adrenergic agonist is an agonist of the receptor α1-adrenergic receptor, selected from the group consisting of: oxymetazoline, tetrahydrozoline, nefazolina, xylometazoline, fenileferina, methoxamine, mephentermine, metaraminol, desglimidodrina midodrina.7 and prodrugs. A method according to claim. 6, wherein the composition comprises from about 0.01% to about 5 wt.% Α1-adrenergic agonist retseptora.8. A method according to claim. 7, wherein the composition comprises from about 0.1% to example1. Способ предупреждения образования кожной опухоли у субъекта, включающий введение субъекту композиции, содержащей эффективное количество агониста α-адренергического рецептора и фармацевтически приемлемый носитель.2. Способ ингибирования прогрессирования существующей кожной