A method for disrupting or destroying selected pathogens located within the body of an organism the method including the non-invasive administration to pre-selected locations on or in the organism of an amount of low intensity ultrasonic energy, effective to disrupt or destroy the selected pathogens but not deleteriously affect the organism, the low intensity ultrasonic energy falling within predefined ranges of frequencies, wherein the predefined range of frequencies is one or more ranges of frequencies at which the low intensity ultrasonic energy has optimal effectiveness in disrupting or destroying a particular pathogen, and the intensity of the low intensity ultrasonic energy falling within predefined ranges of intensity, wherein the predefined range of intensity of low intensity ultrasonic energy is such as to allow for disruption or destruction of the selected pathogens but not deleteriously affect tissue of the organism surrounding the selected pathogens.
