[Problem]Provision of sustained release microparticles having excellent characteristics, in which the microparticles for supporting a substance or substances can fully control the release of the supported substances, can sufficiently diffuse the supported substances in a medium such as water, and can effect sustained release of more than one kind of the supported substances differing in water solubility, each at the respectively desired rate and also to provide preparations which contain said sustained release microparticles.[Means of Solution]Sustained release microparticles comprising a supported substance, microgranular form and coating agent, said microgranular form having an average particle size within a range of from 20 to 300 μm and preparations which contain the sustained release microparticles.