BAHRENBERG, GREGOR,SCHRODER, WOLFGANG,KUHNERT, SVEN
申请号:
NZ59556910
公开号:
NZ595569A
申请日:
2010.03.09
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein are mercaptoquinoline compounds of the formula (1), wherein the variables are defined in the specification, and the use thereof in the treatment of pain, epilepsy, anxiety, dependency, mania, bipolar disorders, migraine, cognitive diseases, dystonia-associated dyskinesias and/or urinary incontinence. Exemplary compounds include: 2-cyclohexyl-N-(2-(2-(phenylsulfonyl)ethylthio)quinolin-3-yl)acetamide; N-(2-(ethylthio)quinolin-3-yl)-3,3-dimethylbutanamide; 3-cyclopentyl-N-(2-ethylsulfanyl-quinolin-3-yl)-propionamide; and N-[2-ethylsulfanyl-4-methyl-7-(trifluoromethyl)-quinolin-3-yl]-2-thiophen-2-yl-acetamide.