Present invention description includes the composition and method natural and artificial surfaces of the what treatment comprising bacterial biof iotalm of novel homogeneous microparticle suspension, it includes the concertedness or humidification between bismuth-mercaptan (BT) compound and certain antibiotic beyond expection, to provide the preparation including antibiotic preparation. Invention further describes the antibacterial properties that do not predict before disclosed BT compounds and BT compounds+antibiotic combinations and antibiont film characters comprising certain this compositions are to preferential effect and certain this compositions for treating certain gram positive bacteria infections to the different preferential effects for treating certain gram positive bacterial infections.本發明描述包括新型均勻微粒懸浮液的組合物和方法用於治療包含細菌生物膜的天然以及人造表面，其包括鉍-硫醇(BT)化合物和某些抗生素之間預料之外的協同性或增强作用，以提供包括抗菌製劑在內的製劑。本發明還描述了公開的BT化合物和BT化合物+抗生素組合的之前未預測的抗菌性質和抗生物膜性質，其包括某些這種組合物對治療某些革蘭氏陽性菌感染的優先功效和某些這種組合物對治療某些革蘭氏陰性菌感染的不同的優先功效。
