A method of treating a pathologic lesion, such as an intravascular thrombus, is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associates with the pathologic lesion； and providing electromagnetic energy via at least one inductive element to the pathologic lesion to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by the pathologic lesion. A shaping device, comprising a flexible segment for encompassing the distal end of a guide wire or catheter； a handle coupled to the flexible segment； andsurface markings to allow measurements from a terminal portion of the guide wire. A catheter, comprising: a hollow tube for insertion into a hollow organ or blood vessel；a guide wire； and a first inductive element disposed on a distal end of the guide wire, the first inductive element receiving an electric current and having a diameter of less than 0.105 inches. A catheter comprising: a guide wire having a radius less than 0.0525 inches； and a coil means for providing electromagnetic energy, the coil means comprised of at least one conductive wire disposed on a distal end of the guide wire, the coil means having a diameter of less than 0.105 inches, the conductive wire having a diameter of less than 0.050 inches.
