A composition including a mixture of at least two different forms of propolis is used to treat a variety of medical conditions. The composition can be administered topically, orally, by inhalation or parenterally. The composition is useful in treating wounds, infections, diabetes, skin conditions, renal conditions, dehydration, malnutrition, hypertension and various other conditions. It has been found that the mixture of at least two different types of propolis, either alone or in combination with other natural products is more effective than the administration of single propolis.