TARGETED EXTRACELLULAR VESICLES COMPRISING MEMBRANE PROTEINS WITH ENGINEERED GLYCOSYLATION SITES

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专利权人:

Northwestern University

发明人:

Joshua N. Leonard,Michelle E. Hung

申请号：

US15278568

公开号：

US20170087087A1

申请日:

2016.09.28

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Disclosed are extracellular vesicles comprising an engineered targeting protein for targeting the extracellular vesicles to target cells. The targeting protein is a fusion protein that includes a ligand, an engineered glycosylation site, and an exosome-targeting domain. Exemplary extracellular vesicles may include but are not limited to exosomes.

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