Flynn, Daniel L.,Kaufman, Michael D.,Smith, Bryan,Rudoltz, Marc S.
申请号：
AU20130404949
公开号：
AU2013404949(B2)
申请日:
2013.11.07
申请国别(地区):
澳大利亚
年份:
2018
代理人:
摘要：
The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1Hpyrazol- 5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
