AYRAL-KALOUSTIAN, SEMIRAMIS,RICHARD, DAVID J,SHI, MENGXIAO,VENKATESAN, ARANAPAKAM M,VERHEIJEN, JEROEN C,ZASK, ARIE,CHEN, ZECHENG,CURRAN, KEVIN J,DEHNHARDT, CHRISTOPH M,DELOS SANTOS, EFREN GUILLERMO,DO
申请号：
MYPI 2010005448
公开号：
MY155653A
申请日:
2009.05.21
申请国别(地区):
MY
年份:
2015
代理人:
摘要：
COMPOUNDS OF FORMULA I: WHEREIN: R1 IS AND R2, R4, AND R6-9 ARE DEFINED HEREIN, AND PHARMACEUTICALLY ACCEPTABLE SALTS AND ESTERS THEREOF. THESE COMPOUNDS INHIBIT P13 KINASE AND mTOR, AND MAY BE USED TO TREAT DISEASES MEDIATED BY P13 KINASE AND mTOR, SUCH AS A VARIETY OF CANCERS. METHODS FOR MAKING AND USING THE COMPOUNDS OF THIS INVENTION ARE DISCLOSED. VARIOUS COMPOSITIONS CONTAINING THE COMPOUNDS OF THIS INVENTION ARE ALSO DISCLOSED.
