SEMIRAMIS AYRAL KALOUSTIAN,ZECHENG CHEN,KEVIN JOSEPH CURRAN,CHRISTOPH MARTIN DEHNHARDT,EFREN GUILLERMO DELOS SANTOS,OSVALDO DOS SANTOS,ARIAMALA GOPALSAMY,JOSHUA AARON KAPLAN,TAREK SUHAYL MANSOUR,DAVID
申请号:
IN7519/DELNP/2010
公开号:
IN2010DN07519A
申请日:
2010.10.26
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
R1 is and R2, R4, and R6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PIS kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed.