TRIAZINE COMPOUNDS AS P13 KINASE AND MTOR INHIBITORS

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专利权人:

WYETH LLC

发明人:

VENKATESAN, ARANAPAKAM, M.,CHEN, ZECHENG,DEHNHARDT, CHRISTOPH, M.,DOS SANTOS, OSVALDO,DELOS, SANTOS, EFREN, GUILLERMO,ZASK, ARIE,VERHEIJEN, JEROEN, C.,KAPLAN, JOSHUA, AARON,RICHARD, DAVID, J.,AYRAL-KA

申请号：

RSP20170476

公开号：

RS55960B1

申请日:

2009.05.21

申请国别(地区):

RS

年份:

2017

代理人:

摘要：

TRIAZINE COMPOUNDS AS PI3 KINASE AND MTOR INHIBITORS Compounds of formula I wherein: R 1 is and R 2 , R 4 , and R 6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed.

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