Methods, systems and cloud processing are provided for coordinating and processing user input provided to vehicles during use. One example is for processing voice inputs at a vehicle to identify a mood of a user and then modifying or customizing the vehicle response based on the detected mood, physical characteristic and/or physiological characteristic of the user. One example includes a vehicle having an on-board computer for processing voice input. The vehicle having a microphone interfaced with the on-board computer and memory for storing a sample of audio data received from the microphone. The audio data is a voice input directed to the vehicle. A processor of the on-board computer is configured to process the sample of audio data to identify markers in frequency and/or magnitude. The markers are used to define an audio signature for the voice input, and the audio signature is used to identify a voice profile. The voice profile is used to identify a vehicle response for the voice input, and the voice prof
