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Single-chain TRAIL receptor agonist proteins
专利权人:
AbbVie Inc.;Apogenix AG
发明人:
HILL, Oliver,THIEMANN, Meinolf,BUCHANAN, Fritz, G.,PHILLIPS, Darren, C.,LAPPE, Susan, E.,GIEFFERS, Christian
申请号:
DK15721089
公开号:
DK3134430T3
申请日:
2015.04.23
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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