HILL, Oliver,GIEFFERS, Christian,THIEMANN, Meinolf,BUCHANAN, Fritz G.,PHILLIPS, Darren C.,LAPPE, Susan E.
申请号：
AU2020202247
公开号：
AU2020202247A1
申请日:
2020.03.30
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020202247A120200423.pdf#####SINGLE-CHAIN TRAIL-RECEPTOR AGONIST PROTEINS ABSTRACT Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
