SEL DE CHLORHYDRATE DE ((1S, 2S, 4R) -4- {4- [(1S) -2,3-DIHYDRO-1H-INDEN-1-YLAMINO] -7H-PYRROLO [2,3-D] PYRIMIDIN-7-YL} -2-HYDROXYCYCLOPENTYL) MÉTHYL SULFAMATE

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专利权人:

Inc.;Millennium Pharmaceuticals

发明人:

申请号：

EP16159438.7

公开号：

EP3091020A3

申请日:

2010.05.13

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Disclosed is a compound of formula ( I ):crystalline forms thereof, and solvates thereof； pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent； and the use of a compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.

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