IAN G. ARMITAGE,MARIANNE LANGSTON,MARTIN IAN COOPER,REENU CHOPRA
申请号:
BRPI1012142
公开号:
BRPI1012142A2
申请日:
2010.05.13
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Disclosed is a compound of formula ( I ): crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.