((1s, 2s, 4r) -4- {4 - [(1s) -2,3-dihydro-1h-inden-1-ylamino] -7h-pyrrolo [2,3-d] pyrimidin-7 hydrochloride salt -yl} -2-hydroxycyclopentyl) methyl sulfamate

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专利权人:

MILLENNIUM PHARMACEUTICALS; INC.

发明人:

IAN G. ARMITAGE,MARIANNE LANGSTON,MARTIN IAN COOPER,REENU CHOPRA

申请号：

BRPI1012142

公开号：

BRPI1012142A2

申请日:

2010.05.13

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

Disclosed is a compound of formula ( I ): crystalline forms thereof, and solvates thereof； pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent； and the use of a compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.

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