Reenu Chopra;Ian G. Armitage;Martin Ian Cooper;Marianne Langston;Steven P. Langston;Stepan Vyskocil
发明人:
Ian G. Armitage,Reenu Chopra,Martin Ian Cooper,Marianne Langston,Steven P. Langston,Stepan Vyskocil
申请号:
US12779331
公开号:
US09187482B2
申请日:
2010.05.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed is a compound of formula (I):crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula (I), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula (I), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.