the present invention, a variety of stem cell types (for example, bone marrow-derived mesenchymal stem cells (BM-MSC) and adipose tissue-derived mesenchymal stem cells (AT-MSC)) is, depending on the culture substrate, lung epithelial marker 5 relates to the discovery that causes a large change in the expression. The invention of the mesenchymal stem cells such as bone marrow and adipose tissue mesenchymal stem cells, lung cells, methods and compositions for the differentiation of the population of lung cells, as well as to reduce or treat a lung abnormality in a subject in need thereof including the way本発明は、さまざまな幹細胞型(例えば、骨髄由来間葉幹細胞(BM-MSC)および脂肪組織由来間葉幹細胞(AT-MSC))が、その培養基材に依って、肺上皮マーカー5発現の大きな変化を起こすという発見に関する。本発明は骨髄および脂肪組織間葉幹細胞のような間葉幹細胞の、肺細胞、肺細胞の集団への分化のための方法および組成物、ならびにその必要のある対象において肺異常を軽減または処置する方法を含む。
