DUFFY, KEVIN J.,杜凯文,杜凱文,FITCH, DUKE M.,费杜克,費杜克,SHAW, ANTONY N.,安东尼,安東尼,WIGGALL, KENNETH,卫格尔,衛格爾,JIN, JIAN,金坚,金堅,LIU, RONGGANG,刘容刚,劉容剛
申请号：
TW096122207
公开号：
TWI394747B
申请日:
2007.06.21
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of fomula (I)which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.本發明係有關式(I)之特定嘧啶三酮N－經取代之甘胺酸衍生物其係HIF脯胺醯基羥化酶之拮抗劑，且適用於治療可因抑制此酵素而受益之疾病，其中一例為貧血。
