經取代之6-(1H-吡唑-1-基)嘧啶-4-胺衍生物及其用途农业专利-农业学术服务平台

发明人:: GIESE, ANJA,吉斯　安佳,KLAR, JUERGEN,克拉尔　乔冈,克拉爾　喬岡,EHRMANN, ALEXANDER,埃尔曼　亚历山大,埃爾曼　亞歷山大,WILLWACHER, JENS,威尔瓦契　詹恩斯,威爾瓦契　詹恩斯,ENGEL, DAVID,安格尔　大卫,安格爾　大衛,DIESKAU, ANDRE PHILIPPE,迪斯考　安德烈,KAHNERT,,吉斯安佳,克拉尔乔冈,克拉爾喬岡,埃尔曼亚历山大,埃爾曼亞歷山大,威尔瓦契詹恩斯,威爾瓦契詹恩斯,安格尔大卫,安格爾大衛,迪斯考安德烈

摘要：: The present invention covers substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular and renal diseases, as a sole agent or in combination with other active ingredients.本發明係涵蓋本文所述及定義之通式(I)之6-(1H-吡唑-1-基)嘧啶-4-胺化合物，製備該等化合物之方法、可作為製備該等化合物之中間化合物，包含該等化合物之醫藥組成物及組合物，及該等化合物作為單一藥劑或與其他活性成分組合之用途，其用於製造供治療或預防疾病、特別是治療及/或預防心血管及腎臟疾病之醫藥組成物。