GARY MARK COPPOLA,YUKI IWAKI,TOSHIO KAWANAMI,RAJESHRI GANESH KARKI,GARY MICHAEL KSANDER,MUNETO MOGI,ROBERT SUN
申请号:
PT10720165
公开号:
PT2435409E
申请日:
2010.05.26
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 5 , B 1 , X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.