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METHOD FOR EARLY DETERMINING DISEASE GRAVITY AND ESTIMATING SEPSIS TREATMENT PROCESS AND ALSO MEANS FOR IMPLEMENTING THIS METHOD
专利权人:
B.R.A.KH.M.S. DIAGNOSTIKA GMBKH
发明人:
KLOD BOKHUON
申请号:
RU19950108591
公开号:
RU2137130(C1)
申请日:
1993.08.19
申请国别(地区):
俄罗斯
年份:
1999
代理人:
摘要:
FIELD: septic diseases. SUBSTANCE: one determines level of peptide procalcitonine and/or incomplete peptide (unripe calcitonin) formed from procalcitonin, presence or amount of determined peptide being indicative of presence of sepsis, its gravity, and/or success of therapy. Determination is accomplished by the aid of immunometric analysis involving at least two monoclonal antibodies or combination of the first monoclonal or polyclonal antibody with the second monoclonal antibody possessing specificity for procalcitonine or procalcitonine-origin peptides. These antibodies are components of procalcitonine diagnostics kit in amounts from 0.1 to 500 ng per 1 ml of plasma or serum sample. EFFECT: increased diagnosis accuracy for earlier phases of sepsis. 14 cl, 2 tbl, 2 ex
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