BEATTIE, DAVID,BRUCE, IAN,COLSON, ANNY-ODILE,CULSHAW, ANDREW JAMES,SHARP, THOMAS
申请号：
ES11701824
公开号：
ES2527849T3
申请日:
2011.01.31
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Compound of formula I； ** Formula ** in which R1 is a group A or B: ** Formula ** in which X1 is C1 to 10 haloalkyl； X2 is halogen； X3 is halogen or haloalkyl； X4 is C1 to 10 alkyl, and (1) when R1 is a group A R4 is a group of formula II or R4 together with R5 and the nitrogen to which they are attached forms a group of formula III； ** Formula ** R5 is hydrogen or together with R4 and the nitrogen to which they are attached forms a group of formula III； X5 is O or -CH2-； X6 is O or -CH2-； R6 is halophenyl, optionally substituted with C1 to 6 alkoxy； R7 is C1 to 6 alkyl； R8 is hydrogen or pyridin-3-yl； R9 is hydrogen or methyl； R10 is -COOH or -CHR36COOH； R12 is hydrogen, C1 to 6 alkyl, C1 to 6 alkoxy, C1 to 6 hydroxyalkyl, -CO2R11 or phenyl optionally substituted with fluorine； R11 is C1 to 6 alkyl； R13 is hydrogen, C1 to 6 alkyl or chlorine； R14 is hydrogen, C1 to 6 alkyl, methoxy, C1 to 6 hydroxyalkyl, ethoxycarbonyl, pyridyl, benzo [1,3] dioxo-5-yl or phenyl, optionally substituted with fluorine, C1 to 6 alkoxy； R15 is hydrogen or methyl； R16, R17, R18, R19, R20, which may be the same or different, are each hydrogen or C1 to 6 alkyl； R21 is C1 to 6 alkyl； R22 is C1 to 6 haloalkyl； R36 and R37, which may be the same or different, are each hydrogen or C1 to 6 alkyl； (2) when R1 is a group B: R4 is a group of formula IV or R4 together with R5 and the nitrogen to which they are attached forms a group of formula V； **Formula**Compuesto de fórmula I； **Fórmula** en la que R1 es un grupo A o B:**Fórmula** en el que X1 es haloalquilo C1 a 10； X2 es halógeno； X3 es halógeno o haloalquilo； X4 es alquilo C1 a 10；y (1) cuando R1 es un grupo A R4 es un grupo de fórmula II o R4 junto con R5 y el nitrógeno al que están unidos forma un grupo de fórmula III； **Fórmula** R5 es hidrógeno o junto con R4 y el nitrógeno al que están unidos forma un grupo de fórmula III； X5 es O o -CH2-； X6 es O o -CH2-； R6 es halofenilo, opcionalmente sustituido con alcoxilo C1 a 6； 5 R7 es alquilo C
