Katherine S. Bowdish,Shana Frederickson,Mark Renshaw
申请号:
US14264975
公开号:
US09409964B2
申请日:
2014.04.29
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Antibodies or fragments thereof having CDR regions replaced or fused with biologically active peptides are described. Flanking sequences may optionally be attached at one or both the carboxy-terminal and amino-terminal ends of the peptide in covalent association with adjacent framework regions. Compositions containing such antibodies or fragments thereof are useful in therapeutic and diagnostic modalities.