Katherine S. Bowdish,Mark Renshaw,Shana Frederickson
申请号:
US12321828
公开号:
US08771932B2
申请日:
2009.01.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Antibodies or fragments thereof having CDR regions replaced or fused with biologically active peptides are described. Flanking sequences may optionally be attached at one or both the carboxy-terminal and amino-terminal ends of the peptide in covalent association with adjacent framework regions. Compositions containing such antibodies or fragments thereof are useful in therapeutic and diagnostic modalities.