JONES, FRANK R.,BALINT, JOSEPH,GODFREY, WAYNE,GABITZSCH, ELIZABETH
申请号:
CA3026345
公开号:
CA3026345A1
申请日:
2017.06.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as a HER2/neu antigen or epitope. In particular embodiments there may be provided methods for constructing and producing recombinant adeno virus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as a HER2/neu antigen or epitope that allow for vaccinations in individuals with preexisting immunity to adenovirus.