JONES, Frank, R.,BALINT, Joseph,GODFREY, Wayne,GABITZSCH, Elizabeth
申请号:
EP17807584
公开号:
EP3464560A4
申请日:
2017.06.02
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as a HER2/neu antigen or epitope. In particular embodiments there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as a HER2/neu antigen or epitope that allow for vaccinations in individuals with preexisting immunity to adenovirus.