JONES, FRANK R.,BALINT, JOSEPH,GABITZSCH, ELIZABETH
申请号：
CA3063747
公开号：
CA3063747A1
申请日:
2018.06.02
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof. In particular embodiments, there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof, that allow for vaccinations in individuals with preexisting immunity to adenovirus.
