WEBER, COLLIN J.,SAFLEY, SUSAN A.,GORDON, KEREEN S.,SIMPSON, NICHOLAS E.
申请号：
EP12760463
公开号：
EP2717862A4
申请日:
2012.03.14
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
This disclosure relates to compositions and methods for encapsulating biomaterials such as cells to prevent immune responses. In certain embodiments, the disclosure relates to capsules comprising a cell or cells gelled in alginate coated with a layer that prevents migration of immune molecules to the cell surface and an outer capsule layer comprising non-immunogenic material optionally containing immunosuppressive agents. In certain embodiments, the cells are capable of generating insulin that emanates from the capsule.
