Kereen S. Gordon;Collin J. Weber;Nicholas E. Simpson;Susan A. Safley
发明人:
Collin J. Weber,Susan A. Safley,Kereen S. Gordon,Nicholas E. Simpson
申请号：
US14000471
公开号：
US20140105974A1
申请日:
2012.03.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This disclosure relates to compositions and methods for encapsulating biomaterials such as cells to prevent immune responses. In certain embodiments the disclosure relates to capsules comprising a cell or cells gelled in alginate coated with a layer that prevents migration of immune molecules to the cell surface and an outer capsule layer comprising non-immunogenic material optionally containing immunosuppressive agents. In certain embodiments, the cells are capable of generating insulin that emanates from the capsule.
