PURPOSE: A fermented red ginseng composition containing red ginseng and herb extract with anti-diabetic activity is provided to ensure blood glucose reduction, sugar resistance, and anti-oxidation and to prevent and treat diabetes and complication. CONSTITUTION: A composition for preventing and treating diabetes and complication contains fermentation which is obtained by fermenting extract of 100 weight parts of Red Ginseng, 5-85 weight parts of Mulberry leaves, 5-85 weight parts of Moris alba L., 5-75 weight parts of Angelica gigas N., 5-75 weight parts of Poria cocos Wolf and 5-75 weight parts of Araliae Cortex using Lactobacillus. The Lactobacillus is Lactobacillus fermenturm NUC-C1 KCCM10929P.본 발명은 항당뇨 활성을 갖는 발효홍삼 및 약용식물 추출물 함유 발효홍삼 조성물에 관한 것으로 상세하게는 홍삼(Red Ginseng)을 Lactobacillus fermentum NUC-C1KCCM10929P로 발효시킨 발효홍삼과 상엽(Mulberry leaves, Mori folium), 상백피(Moris alba L.), 당귀(Angelica gigas N.), 백복령(Poria cocos Wolf), 총목피(Araliae Cortex)로 혼합 구성된 약용식물추출물을 첨가한 홍삼을 Lactobacillus fermentum NUC-C1KCCM10929P로 발효시킨 발효물로써 혈당강하, 당내성, 인슐린분비 촉진 활성, 항산화, 지질대사개선 효과가 우수하여 당뇨 및 합병증 예방, 치료에 유용한 약학 및 건강기능식품조성물로 사용될 수 있다.
