The invention relates to compounds of natural origin and to the pharmaceutically acceptable, active mixture thereof for the reduction of high levels of glucose, cholesterol, uric acid and body fat, cytoprotection of damaged organs, activation of the metabolism and cell proliferation. The invention is illustrated with the example of a pharmaceutical composition comprising a pharmaceutically effective quantity of the compounds of formulation I, and the method for using same in in vitro and in vivo systems. Formulation I and the variables thereof can be used to treat hyperglycemia, gout, dyslipidemia, obesity, insulin resistance, diabetes mellitus, diabetes insipidus, type 1 diabetes, type 2 diabetes, microvascular complications, macrovascular complications, lipid disorders, prediabetes, arrhythmias, myocardial infarction, renal and pancreatic complications, cardiovascular complications.