Detecting isotopes and determining isotope ratios using raman spectroscopy

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专利权人:

FINK MANFRED F.;VARGHESE PHILIP L.

发明人:

FINK MANFRED F.,VARGHESE PHILIP L.

申请号：

US20020234418

公开号：

US2003053049(A1)

申请日:

2002.09.03

申请国别(地区):

美国

年份:

2003

代理人:

摘要：

The methods and apparatus described may be used for the discrimination of two closely spaced spectral lines. In certain embodiments the methods and apparatus may be used for the detection of isotopes and isotopic ratios by Raman spectroscopy. In certain embodiments the conversion of a labeled substrate to a labeled product may be detected. In particular embodiments the conversion of a 13C labeled substrate to a 13C labeled product may be detected. In other embodiment the conversion of 13C urea to 13CO2 is detected. Embodiments described include the diagnostic determination of 13CO2/12CO2 ratio in a test sample.

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