KEHRY, Marilyn,KING, David, J.,LING, Leona, E.,MEADOR, James III,ROY, Sucharita,MANNING, Anthony
申请号:
SG11201705475Q
公开号:
SG11201705475QA
申请日:
2016.01.29
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
The present invention features antibodies that have high binding affinity to human neonatal Fc receptor (FcRn). These anti-FcRn antibodies are useful, e.g., to promote clearance of autoantibodies in a subject, to suppress antigen presentation in a subject, to block an immune response, e.g., block an immune complex-based activation of the immune response in a subject, and to treat immunological diseases (e.g., autoimmune diseases) in a subject.