KEHRY, MARILYN,KING, DAVID J.,LING, LEONA E.,MEADOR, JAMES, III,ROY, SUCHARITA,MANNING, ANTHONY
申请号:
CA2972822
公开号:
CA2972822A1
申请日:
2016.01.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention features antibodies that have high binding affinity to human neonatal Fc receptor (FcRn). These anti-FcRn antibodies are useful, e.g., to promote clearance of autoantibodies in a subject, to suppress antigen presentation in a subject, to block an immune response, e.g., block an immune complex-based activation of the immune response in a subject, and to treat immunological diseases (e.g., autoimmune diseases) in a subject.